[SignalChem Diagnostics 공식대리점 관련 업무대행/수입] PsmCas13b

[SignalChem Diagnostics 공식대리점 관련 업무대행/수입] PsmCas13b

[PsmCas13b]

Product Overview:

• Alternate Names: CRISPR-associated ribonuclease Cas13b
• Accession Number: WP_036929175.1
• Formulation: Protein stored in 25mM Tris, 300mM NaCl pH7.5 50% glycerol 0.1mM TCEP
• Storage and Stability: Store at –20°C. To avoid repeated handling and multiple freeze/thaw cycles aliquot diluted product into smaller quantities.
• Concentration: 0.8 μg/μl, 6.26 pmol/μg
• Purity: >90%
• Molecular Weight: Calculated: 156.7 kDa, Observed: ~155 kDa

References:

1. Horvath, P., et al. 2010. CRISPR/Cas, the immune system of bacteria and archaea. Science, 327(5962):167-170.
2. Morange, M. 2015. What history tells us XXXVII. CRISPR-Cas: The disconvery of an immune system in prokaryotes. J. Biosci. 40(2):221-223.
3. Smargon, A. A., et al. 2017. Cas13b is a Type VI-B CRISPR-associated RNA-Guided RNAse differentially regulated by accessory proteins Csx27 and Csx28. Mol. Cell. 65(4):618-630.
4. Freije, C. A., et al. 2019. Programmable Inhibition and Detection of RNA Viruses Using Cas13. Mol. Cell. 76(5):826-837.